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威而鋼是海綿體中cGMP特異性磷酸二酯酶5型（PDE5）的有效和選擇性抑製劑，其中PDE5負責cGMP的降解。威而鋼對勃起有作用的外圍部位。威而鋼對分離的人海綿體沒有直接的鬆弛作用，但有效增強了NO對這種組織的鬆弛作用。當NO / cGMP途徑被激活時（如發生性刺激時一樣），威而鋼對PDE5的抑製作用會導致cGMP海綿體水平增加。因此，為了使威而鋼產生預期的有益藥理作用，需要性刺激。
在臨床試驗中，82%服用100毫克威而鋼的男性勃起得到改善。如果患有中度至重度ED，或者對較低劑量的藥物沒有反應，通常會使用這種劑量的威而鋼。就像服用50毫克威而鋼一樣，服用100毫克威而鋼可能會出現副作用，包括面部潮紅、胃部不適、鼻塞、視力異常、血管舒張和頭痛。威而鋼、專家告訴你如何提高性能力
I never write reviews and today, I’ve written 2! One on some baby girl long sleeve rompers spoons and now this! I purchased the cherry ensemble and I love it! The entire outfit is absolutely adorable and YOU WILL want to come back and purchase the other dresses that you presently have your eye on. So, just go ahead and get them all now in one shot! Your princess will get plenty of compliments, so be prepared! I only wish that it had buttons in the back to so that she could get a little more wear out of it, now that I have to tug it over her head to get on. The dress is fine, it’s just that she’s grown and I’m still trying to get it over her head. Really, I just need to buy another one! It’s worth it.
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